Molecular Neurodegeneration Course - Hinxton, Cambridgeshire

External Event - 14th to 18th Jan 2019

Wellcome Trust Genome Campus, Hinxton, Saffron Walden CB10 1SA, United Kingdom

This course provides an overview of the molecular basis of neurodegeneration and the development of therapeutic intervention to combat neurodegenerative disorders. The programme will cover several neurological disorders including Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, Fragile X, Spinocerebellar ataxia and amyotrophic lateral sclerosis. It will highlight experimental techniques used in neurogenetics and stem cell research. The course will provide an introduction to bioinformatic approaches relevant to neurology, including genome-wide association studies.

Participants will gain an insight into the current understanding of both rare and common neurological disorders, the strengths and weaknesses of experimental approaches and evidence, and how this knowledge can be applied to develop therapies.

The programme is aimed at individuals working in neurodegenerative research, neurogenetics or translational neuroscience, including clinical scientists, veterinary scientists, PhD students and post-doctoral researchers. We encourage applications from researchers based in the pharmaceutical and biotechnology industries. Applications from those who have completed a PhD in another area and have moved into neuroscience for their postdoctoral studies will also be considered.

The course will benefit researchers who seek a comprehensive view of neurodegenerative disorders together with state of the art research techniques, and who wish to gain a new perspective on their own studies. The intensive programme provides the opportunity to interact with leading neuroscientists. To optimize discussions and interactions, numbers are limited to 30 students.

Learning outcomes

After attending this course, participants will be able to:

• Describe in detail the process of neurodegeneration
• Discuss and contrast different neurodegenerative disorders
• Critique the impact and limitations on the use of big data in the field of neurodegeneration
• Interpret and communicate the findings of genomics studies from single cells to large populations
• Critically evaluate the advantages and disadvantages of varying disease models, from fly models to patient-derived iPSCs
• Describe recent advances in therapeutic and translational areas to prevent and treat neurodegenerative diseases
• Apply concepts learned on the course to your own research project

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